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Product Name
Human Prealbumin/Transthyretin (His Tag) recombinant protein
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Description
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
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Protein name
Transthyretin
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Protein short names
ATTR; HEL111; TTR; CTS; D17860; TRANSTHYRETIN; AA408768; PALB; CTS1; MGC107649; TBPA; PREALBUMIN; HST2651; AI787086
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Uniprot ID
P02766
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Gene Name
HEL111; TTR; hCG_25470
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human TTR (NP_000362.1) (Met 1-Glu 147) with a C-terminal polyhistidine tag was expressed.
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Protein Species
Human
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Molecular weight
The secreted recombinant human TTR comprises 138 amino acids with a predicted molecular mass of 15.2 kDa. As a result of glycosylation, the apparent molecular mass of rhTTR is approximately 19 and 38 kDa in SDS-PAGE under reducing conditions, corresponding to the monomer and dimer respectively.
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Purity
> 97 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA.
Immobilized recombinant human TTR-His (Cat:502712)at 10 μg/ml (100 μl/well) can bind recombinant Canine RBP4-Fc (Cat:504671) with a linear range of 0.3-10.0 μg/ml. -
Validations
Human Prealbumin / Transthyretin / TTR / PALB Protein (His Tag) SDS-PAGE
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