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transgelin/SM22 antibody

Cat.#: 107640

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Product Information

  • Product Name
    transgelin/SM22 antibody
  • Documents
  • Description
    transgelin/SM22 Mouse Monoclonal antibody. Positive IHC detected in human colon tissue, human heart tissue. Positive WB detected in Human colon, human stomach tissue. Observed molecular weight by Western-blot: 18+22 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    SM22 antibody; SM22 alpha antibody; SM22a antibody; SM22-a antibody; SM22alpha antibody; Smooth muscle protein 22 alpha antibody; TAGLN antibody; TAGLN1 antibody; transgelin antibody; transgelin/SM22 alpha antibody
  • Immunogen
    Human TAGLN Recombinant protein (GST tag)
  • Isotype
    Mouse IgG1
  • Preparation
    This antibody was obtained by immunization of transgelin/SM22 recombinant protein (Accession Number: NM_003186). Purification method: Protein G purified.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    human colon tissue were subjected to SDS PAGE followed by western blot with Catalog No:107640(TAGLN antibody) at dilution of 1:1000

    human colon tissue were subjected to SDS PAGE followed by western blot with Catalog No:107640(TAGLN antibody) at dilution of 1:1000

    Immunohistochemistry of paraffin-embedded human colon tissue slide using Catalog No:107640(TAGLN Antibody) at dilution of 1:200 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human colon tissue slide using Catalog No:107640(TAGLN Antibody) at dilution of 1:200 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human colon tissue slide using Catalog No:107640(TAGLN Antibody) at dilution of 1:200 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human colon tissue slide using Catalog No:107640(TAGLN Antibody) at dilution of 1:200 (under 40x lens)

  • Background
    The transgelin family is a group of proteins that belong to 22kd actin-related corpnin superfamily. Of all three isoforms, transgelin 1 is the best characterized. Transgelin 1, also known as SM22alpha, is a specific marker for differentiated smooth muscle cells. Transgelin 2, also known as SM22 beta, is expressed by both smooth muscle and non-smooth muscle cells in a temporally and spatially regulated pattern. Trangenlin 3, also known as NP25, is only found in highly differentiated neuronal cells.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"