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Product Name
Human TLE3 (aa 484-772, GST Tag) recombinant protein
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Description
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
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Protein name
Transducin-like enhancer protein 3
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Protein short names
FLJ39460; TLE3; HST18976; 2610103N05RIK; GRG3B; ESG3; MKIAA1547; GRG3; ESG; KIAA1547; GRG3A
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Uniprot ID
Q04726
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Gene Name
TLE3; KIAA1547
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the N-terminal fragment of human TLE3 (Q04726-1) (Ser 484-Tyr 772) was fused with the GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human TLE3/GST chimera consists of 520 amino acids and has a predicted molecular mass of 58.5 kDa as estimated in SDS-PAGE under reducing conditions.
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Purity
> 78 % as determined by SDS-PAGE
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Validations
Human TLE3 Protein (aa 484-772, GST Tag) SDS-PAGE
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