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Product Name
TPPP antibody
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Description
TPPP Rabbit Polyclonal antibody. Positive IHC detected in human spleen tissue. Positive WB detected in mouse brain tissue, MCF7 cells, mouse spleen tissue. Observed molecular weight by Western-blot: 24-28kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
25 kDa brain specific protein antibody; p24 antibody; p25 antibody; p25 alpha antibody; p25alpha antibody; TPPP antibody; TPPP/p25 antibody; TPPP1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: XM_047416674). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116211(TPPP antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human spleen using Catalog No:116211(TPPP antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human spleen using Catalog No:116211(TPPP antibody) at dilution of 1:100 (under 40x lens)
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Background
TPPP, also named as TPPP1, P24 and P25, belongs to the TPPP family. TPPP promotes in vitro the polymerization of tubulin into double-walled tubules and polymorphic aggregates or bundled stabilized microtubules blocks. When overexpressed, TPPP inhibits mitotic spindle assembly and nuclear envelope breakdown, apparently without affecting other cellular events.
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