TNNC1 Rabbit Polyclonal antibody. Positive WB detected in human stomach tissue. Positive IHC detected in human heart tissue, human lung tissue. Observed molecular weight by Western-blot: 18 kDa
ELISA, WB, IHC
Human,Mouse,Rat; other species not tested.
CMD1Z antibody; TN C antibody; TNC antibody; TNNC antibody; TNNC1 antibody; troponin C type 1 (slow) antibody
This antibody was obtained by immunization of TNNC1 recombinant protein (Accession Number: NM_003280). Purification method: Antigen affinity purified.
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20℃. DO NOT ALIQUOT
human stomach tissue were subjected to SDS PAGE followed by western blot with Catalog No:116148(TNNC1 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human heart using Catalog No:116148(TNNC1 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human heart using Catalog No:116148(TNNC1 antibody) at dilution of 1:50 (under 40x lens)
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. TnC plays an important role in excitation-contraction coupling and is the primary target of compounds such as levosimendan that augment Ca2+ responsiveness of the thin filament.
- Leung CS, Yeung TL, Yip KP. Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential. Nature communications. 5:5092. 2014.
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