TLR7 Polyclonal Antibody

Cat.#: 160201

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Product Information

  • Product Name
    TLR7 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to TLR7
  • Tested applications
    IHC, IF
  • Species reactivity
    Human, Mouse
  • Alternative names
    TLR7 antibody; TLR7-like antibody; toll-like receptor 7 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-230 of human TLR7 (NP_057646.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    IHC 1:50 - 1:200
    IF 1:50 - 1:200
  • Validations

    Immunohistochemistry - TLR7 Polyclonal Antibody

    Immunohistochemistry - TLR7 Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded human thyroid cancer using TLR7 Antibody at dilution of 1:100 (40x lens).

    Immunohistochemistry - TLR7 Polyclonal Antibody

    Immunohistochemistry - TLR7 Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded mouse brain using TLR7 Antibody at dilution of 1:100 (40x lens).

    Immunofluorescence - TLR7 Polyclonal Antibody

    Immunofluorescence - TLR7 Polyclonal Antibody

    Immunofluorescence analysis of MCF-7 cells using TLR7 antibody . Blue: DAPI for nuclear staining.

  • Background
    Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"