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Product Name
TLR7 Polyclonal Antibody
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Description
Polyclonal antibody to TLR7
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Tested applications
IHC, IF
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Species reactivity
Human, Mouse
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Alternative names
TLR7 antibody; TLR7-like antibody; toll-like receptor 7 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-230 of human TLR7 (NP_057646.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
IHC 1:50 - 1:200
IF 1:50 - 1:200 -
Validations
Immunohistochemistry - TLR7 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human thyroid cancer using TLR7 Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - TLR7 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse brain using TLR7 Antibody at dilution of 1:100 (40x lens).
Immunofluorescence - TLR7 Polyclonal Antibody
Immunofluorescence analysis of MCF-7 cells using TLR7 antibody . Blue: DAPI for nuclear staining.
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Background
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"