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Product Name
TLE1 antibody
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Description
TLE1 Mouse Monoclonal antibody. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 85-95 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
E(Sp1) homolog antibody; ESG antibody; ESG1 antibody; GRG1 antibody; TLE1 antibody
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Isotype
Mouse IgG2b
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Preparation
This antibody was obtained by immunization of TLE1 recombinant protein (Accession Number: NM_005077). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:107625(TLE1 Antibody) at dilution of 1:1000
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Background
Transducin-like enhancer protein 1(TLE1) is a transcriptional corepressor. It can bind to and regress expression of many transcription factors such as NFkB, which is mediated by FOXA2, CTNNB1 and TCF family member in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Expression of TLE1 is highest in skeletal muscle and liver, moderate in placenta, heart, kidney, and spleen, and weak in all other tissues including brain.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"