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Product Name
TEAD4 antibody
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Description
TEAD4 Rabbit Polyclonal antibody. Positive IP detected in MCF-7 cells. Positive WB detected in MDA-MB-453s cells, BGC-823 cells, MCF-7 cells. Observed molecular weight by Western-blot: 65 kDa
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Tested applications
ELISA, IP, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
EFTR 2 antibody; hRTEF 1B antibody; RTEF1 antibody; TCF13L1 antibody; TEA domain family member 4 antibody; TEAD 4 antibody; TEAD4 antibody; TEF 3 antibody; TEF3 antibody; TEFR 1 antibody; Transcription factor 13 like 1 antibody; Transcription factor RTEF 1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TEAD4 recombinant protein (Accession Number: NM_003213). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
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Validations
MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with Catalog No:115934(TEAD4 Antibody) at dilution of 1:600
IP Result of anti-TEAD4 (IP:Catalog No:115934, 3ug; Detection:Catalog No:115934 1:300) with MCF-7 cells lysate 2000ug.
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Background
TEAD4 belongs to a protein family that share the TEA/ATTS domain. The transcriptional activity of TEAD4 required several regions of the proteins , a TBP-associated factors and a limiting transcriptional intermediary facotrs. TEAD4 also preforms an essential role in the Hippo signaling pathway. TEAD4 regulates gene rexpression of YAP1 and WWTR1/TAZ, thus mediating cell proliferation, migration and epithelial mesenchymal transition induction.
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References
- Zhang D, Wang X, Li Y. Thyroid hormone regulates muscle fiber type conversion via miR-133a1. The Journal of cell biology. 207(6):753-66. 2014.
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