TAF1C Polyclonal Antibody

Cat.#: 165026

Special Price 174.2 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    TAF1C Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to TAF1C
  • Tested applications
    WB, IHC
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    TAF1C antibody; MGC:39976 antibody; SL1 antibody; TAFI110 antibody; TAFI95 antibody; TATA box-binding protein-associated factor RNA polymerase I subunit C antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 70-320 of human TAF1C (NP_001230085.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IHC 1:50 - 1:200
  • Validations

    Western blot - TAF1C Polyclonal Antibody

    Western blot - TAF1C Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using TAF1C antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.

    Immunohistochemistry - TAF1C Polyclonal Antibody

    Immunohistochemistry - TAF1C Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded mouse lung using TAF1C Antibody at dilution of 1:100 (40x lens).

    Immunohistochemistry - TAF1C Polyclonal Antibody

    Immunohistochemistry - TAF1C Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded human gastric cancer using TAF1C Antibody at dilution of 1:100 (40x lens).

    Immunohistochemistry - TAF1C Polyclonal Antibody

    Immunohistochemistry - TAF1C Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded mouse lung using TAF1C Antibody at dilution of 1:100 (40x lens).

  • Background
    Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"