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Product Name
Anti-TAF1C Rabbit antibody
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Description
TAF1C Rabbit polyclonal antibody
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Tested applications
WB, IP
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Species reactivity
Human
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Alternative names
SL1; TAFI95; TAFI110; MGC:39976 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human TAF1C
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
IP: 1/20
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Validations
Western blot detection of TAF1C in K562 cell lysates using TAF1C Rabbit pAb(1:1000 diluted).Predicted band size:95kDa.Observed band size:95kDa.
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Background
Swiss-Prot Acc.Q15572.Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"