TACC2 antibody

TACC2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

TACC2 Rabbit Polyclonal antibody. Positive IHC detected in human lung cancer tissue. Positive IF detected in A431 cells. Positive WB detected in mouse testis tissue. Observed molecular weight by Western-blot: 73kd

ELISA, WB, IHC, IF

Human,Mouse,Rat; other species not tested.

Anti Zuai 1 antibody; AZU 1 antibody; ECTACC antibody; TACC2 antibody

Rabbit IgG

This antibody was obtained by immunization of TACC2 recombinant protein (Accession Number: BC015736). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Transforming acidic coiled-coil (TACC) proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. TACC2, also known as anti-zuai-1 (AZU-1), was abundantly expressed in non- and premalignant cells and tissues but was appreciably reduced in breast tumor cell types and in primary tumors, thus TACC2 may act as a tumor suppressor protein and represent a tumor progression marker. Several transcript variants encoding different isoforms have been found for this gene. Chromosome segregation in mitosis is orchestrated by dynamic interaction between spindle microtubule and the kinetochore. Centrosomal TACC2 plays a role in organizing centrosomal microtubules and is required for mitotic spindle maintenance.