-
Product Name
Rat CD8a / Lyt2 (Fc Tag) recombinant protein
- Documents
-
Description
Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
-
Protein name
T-cell surface glycoprotein CD8 alpha chain
-
Protein short names
LY-35; LYT-2; CD8; BB154331; CD8A; LY-B; P32; LY-2; LEU2; MAL
-
Uniprot ID
P07725
-
Gene Name
Cd8a
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the rat CD8A (P07725) (Met1-Tyr189) was expressed with the Fc region of human IgG1 at the C-terminus.
-
Protein Species
Rat
-
Molecular weight
The recombinant rat CD8A/Fc is a disulfide-linked homodimer. The reduced monomer comprises 404 amino acids and has a predicted molecular mass of 45 kDa. The apparent molecular mass of the protein is approximately 46 kDa in SDS-PAGE under reducing conditions due to glycosylation.
-
Purity
> 90 % as determined by SDS-PAGE
-
Validations
Rat CD8A / Lyt2 Protein (Fc Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"