-
Product Name
Human CD28 (Fc Tag) recombinant protein
- Documents
-
Description
Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
-
Protein name
T-cell-specific surface glycoprotein CD28
-
Protein short names
TP44; CH29-189K17.3; MGC138290; CD28
-
Uniprot ID
P10747
-
Gene Name
CD28
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the human CD28 isoform 1 (P10747-1) extracellular domain (Met 1-Pro 152) was was fused with the Fc region of human IgG1 at the C-terminus.
-
Protein Species
Human
-
Molecular weight
The recombinant human CD28/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 375 amino acids and predictes a molecular mass of 42 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhCD28/Fc monomer is approximately 55-65 kDa due to glycosylation.
-
Purity
> 90 % as determined by SDS-PAGE
-
Validations
Human CD28 Protein (Fc Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"