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Sur-8 antibody

Cat.#: 115745

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Product Information

  • Product Name
    Sur-8 antibody
  • Documents
  • Description
    Sur-8 Rabbit Polyclonal antibody. Positive IHC detected in human kidney tissue, human brain tissue, human testis tissue. Positive WB detected in Jurkat cells, MCF7 cells, mouse brain tissue, rat testis tissue, U-251 cells. Observed molecular weight by Western-blot: 65 kDa
  • Tested applications
    ELISA, IHC, WB
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    FLJ60412 antibody; KIAA0862 antibody; Protein sOC 2 homolog antibody; Protein sur 8 homolog antibody; SHOC2 antibody; SIAA0862 antibody; SOC 2 antibody; SOC2 antibody; SUR 8 antibody; SUR8 antibody; sur-8 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Sur-8 recombinant protein (Accession Number: XM_017016704). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:115745(SHoc2 Antibody) at dilution of 1:600

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:115745(SHoc2 Antibody) at dilution of 1:600

    Immunohistochemistry of paraffin-embedded human kidney tissue slide using Catalog No:115745(SHoc2 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human kidney tissue slide using Catalog No:115745(SHoc2 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human kidney tissue slide using Catalog No:115745(SHoc2 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human kidney tissue slide using Catalog No:115745(SHoc2 Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    SHoc2 represents soc-2 suppressor of clear homolog (C. elegans)
  • References
    • Harmon RM, Simpson CL, Johnson JL. Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation. The Journal of clinical investigation. 123(4):1556-70. 2013.
    • Jang ER, Shi P, Bryant J. HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold. Molecular and cellular biology. 34(19):3579-93. 2014.
    • Jang ER, Jang H, Shi P, Popa G, Jeoung M, Galperin E. Spatial control of Shoc2-scaffold-mediated ERK1/2 signaling requires remodeling activity of the ATPase PSMC5. Journal of cell science. 128(23):4428-41. 2015.
    • Jeoung M, Jang ER, Liu J. Shoc2-tranduced ERK1/2 motility signals - Novel insights from functional genomics. Cellular signalling. 28(5):448-459. 2016.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"