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Product Name
Human SULT2B1 (His Tag) recombinant protein
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Description
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol.
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Protein name
Sulfotransferase family cytosolic 2B member 1
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Protein short names
ST2B1; SULT2B1; SULT2B; BB173635; AI326997; HSST2
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Uniprot ID
O00204
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Gene Name
SULT2B1; HSST2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human SULT2B1 (NP_004596.2) (Asp 2-Ser 365) was expressed, with a N-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The recombinant human SULT2B1 comprises 371 amino acids and has a calculated molecular mass of 42 kDa. It migrates as an approximately 44 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 76 % as determined by SDS-PAGE
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Validations
Human SULT2B1 / HSST2 Protein (His Tag) SDS-PAGE
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