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Product Name
STK36 antibody
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Description
STK36 Rabbit Polyclonal antibody. Positive IP detected in mouse testis tissue. Positive WB detected in mouse testis tissue. Positive IHC detected in human prostate tissue. Observed molecular weight by Western-blot: 144 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
DKFZp434N0223 antibody; Fused homolog antibody; KIAA1278 antibody; STK36 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of STK36 recombinant protein (Accession Number: NM_001369423). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:115721(STK36 antibody) at dilution of 1:300
Immunohistochemical of paraffin-embedded human prostate using Catalog No:115721(STK36 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human prostate using Catalog No:115721(STK36 antibody) at dilution of 1:50 (under 40x lens)
IP Result of anti-STK36 (IP:Catalog No:115721, 4ug; Detection:Catalog No:115721 1:500) with mouse testis tissue lysate 4000ug.
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Background
STK36(Serine/threonine-protein kinase 36) is also named as KIAA1278 and belongs to the Ser/Thr protein kinase family. The Serine/threonine protein kinase plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors and controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. It has 2 isoforms produced by alternative splicing.
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References
- Nozawa YI, Yao E, Gacayan R, Xu SM, Chuang PT. Mammalian Fused is essential for sperm head shaping and periaxonemal structure formation during spermatogenesis. Developmental biology. 388(2):170-80. 2014.
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