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Product Name
ST2 antibody
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Description
ST2 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue. Positive IHC detected in human lung cancer tissue, human heart tissue. Observed molecular weight by Western-blot: 30 kDa,40 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
DER4 antibody; FIT 1 antibody; IL1RL1 antibody; interleukin 1 receptor like 1 antibody; Protein ST2 antibody; ST2 antibody; ST2L antibody; ST2V antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ST2 recombinant protein (Accession Number: NM_003856). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:50-1:500
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Validations
Variants of IL1RL1 recognized by Catalog No:115621.
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115621(IL1RL1 antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human lung cancer using Catalog No:115621(IL1RL1 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human lung cancer using Catalog No:115621(IL1RL1 antibody) at dilution of 1:50 (under 40x lens)
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Background
Protein ST2, also known as IL1RL1, is a member of the interleukin 1 receptor family. The gene of ST2 encodes three splice variants: a soluble secreted form, a transmembrane form and a form of undetermined localization.This antibody recognizes at least 80kd, 40kd and 30kd forms in different tissues and cells.
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References
- Li P, Ma H, Han D, Mou K. Interleukin-33 affects cytokine production by keratinocytes in vitiligo. Clinical and experimental dermatology. 40(2):163-70. 2015.
- Maywald RL, Doerner SK, Pastorelli L. IL-33 activates tumor stroma to promote intestinal polyposis. Proceedings of the National Academy of Sciences of the United States of America. 112(19):E2487-96. 2015.
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