-
Product Name
SRP68 antibody
- Documents
-
Description
SRP68 Rabbit Polyclonal antibody. Positive WB detected in human kidney tissue, human brain tissue. Positive IP detected in mouse kidney tissue. Positive IHC detected in human gliomas tissue. Observed molecular weight by Western-blot: 68 kDa
-
Tested applications
ELISA, WB, IHC, IP
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
SRP68 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of SRP68 recombinant protein (Accession Number: BC020238). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:1000
IHC: 1:20-1:200
-
Validations
human kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:115594(SRP68 antibody) at dilution of 1:400
Immunohistochemical of paraffin-embedded human gliomas using Catalog No:115594(SRP68 antibody) at dilution of 1:100 (under 10x lens)
IP Result of anti-SRP68 (IP:Catalog No:115594, 4ug; Detection:Catalog No:115594 1:400) with mouse kidney tissue lysate 4000ug.
-
Background
The signal recognition particle (SRP) is a ribonucleoprotein complex that mediates the targeting of secretory proteins to the rough endoplasmic reticulum (ER) membrane. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. SRP68 is one component of the ribonucleprotein complex, and forms a heterodimer with SRP72.
-
References
- Zhang Y, Yao K, Yu Y. Effects of 1.8 GHz radiofrequency radiation on protein expression in human lens epithelial cells. Human & experimental toxicology. 32(8):797-806. 2013.
- Ren YF, Li G, Xue YF. Decreased dicer expression enhances SRP-mediated protein targeting. PloS one. 8(2):e56950. 2013.
- Piazzon N, Schlotter F, Lefebvre S. Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle. Nucleic acids research. 41(2):1255-72. 2013.
- Rothé B, Saliou JM, Quinternet M. Protein Hit1, a novel box C/D snoRNP assembly factor, controls cellular concentration of the scaffolding protein Rsa1 by direct interaction. Nucleic acids research. 42(16):10731-47. 2014.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"