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Product Name
SOX10 Polyclonal Antibody
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Description
Polyclonal antibody to SOX10
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Tested applications
WB, IHC
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Species reactivity
Human, Mouse, Rat
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Alternative names
SOX10 antibody; DOM antibody; PCWH antibody; WS2E antibody; WS4 antibody; WS4C antibody; SRY-box 10 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic Peptide of human SOX10
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
IHC 1:20 - 1:50 -
Validations
Western blot - SOX10 Polyclonal Antibody
Western blot analysis of extracts of A-375 cells, using SOX10 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"