SOX10 Polyclonal Antibody
Polyclonal antibody to SOX10
SOX10 antibody; DOM antibody; PCWH antibody; WS2E antibody; WS4 antibody; WS4C antibody; SRY-box 10 antibody
Antigen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SOX10 (NP_008872.1).
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Store at -20℃. Avoid freeze / thaw cycles.
WB 1:500 - 1:2000
Western blot - SOX10 Polyclonal Antibody
Western blot analysis of extracts of A-375 cells, using SOX10 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 30s.
Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3.
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