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SNAI2 antibody

Cat.#: 115442

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Product Information

  • Product Name
    SNAI2 antibody
  • Documents
  • Description
    SNAI2 Rabbit Polyclonal antibody. Positive WB detected in mouse pancreas tissue, HepG2 cells. Positive IHC detected in human kidney tissue. Observed molecular weight by Western-blot: 30 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    Protein snail homolog 2 antibody; SLUG antibody; SLUGH antibody; SLUGH1 antibody; SNAI2 antibody; snail homolog 2 (Drosophila) antibody; WS2D antibody; Zinc finger protein SNAI2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of SNAI2 recombinant protein (Accession Number: NM_003068). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:1000

    IHC: 1:20-1:200

  • Validations

    mouse pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:115442(SNAI2 antibody) at dilution of 1:300

    mouse pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:115442(SNAI2 antibody) at dilution of 1:300

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:115442(SNAI2 antibody) at dilution of 1:200 (under 10x lens)

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:115442(SNAI2 antibody) at dilution of 1:200 (under 10x lens)

  • Background
    SNAI2 belongs to the Snail family of zinc finger transcription factors, which shares an evolutionarily conserved role in mesoderm formation in vertebrates and invertebrates. It tiggers epithelial-mesenchymal transitions and has a crucial role in developmental processes. Also it is a transcriptional reperssor in mediating RAF-induced expression of TJ protein, occludin(ocLN) and subsequent oncogenic transformation of epithelial cells
  • References
    • Wang P, Cheng H, Wu J, Yan A, Zhang L. STK33 plays an important positive role in the development of human large cell lung cancers with variable metastatic potential. Acta biochimica et biophysica Sinica. 47(3):214-23. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"