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Product Name
SLMAP antibody
- Documents
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Description
SLMAP Rabbit Polyclonal antibody. Positive WB detected in mouse heart tissue, A431 cells, mouse skeletal muscle tissue. Observed molecular weight by Western-blot: 35, 45, 63-66, 83-91 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
FLJ42206 antibody; KIAA1601 antibody; sarcolemma assOCiated protein antibody; Sarcolemmal assOCiated protein antibody; SLAP antibody; SLMAP antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SLMAP recombinant protein (Accession Number: NM_001304420). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:115409(SLMAP Antibody) at dilution of 1:600
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Background
Sarcolemmal membrane associated protein (SLMAP) is a tail-anchored membrane protein involved in the docking and membrane fusion process via protein-protein interactions. Deregulation of SLMAP expression plays an important role in type 2 diabetes, and changes in SLMAP expression are linked to hyperglycemia and diabetes. SLMAPs are components of cardiac membranes and have been identified as a novel regulator of cardiac function. There are several isoforms of SLMAPs with varying molecular size (35, 45, 63, and 83-91 kDa) as a result of alternative splicing. The short 35-kDa isoform is predominantly expressed in cardiac and slow-twitch skeletal muscle, while the 83- to 91-kDa isoform is ubiquitous. This antibody recognizes all of these isoforms in mouse heart lysate. (21785580, 22180652)
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