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Product Name
SLC27A2 Polyclonal Antibody
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Description
Polyclonal antibody to SLC27A2
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Tested applications
WB, IHC
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Species reactivity
Human, Mouse
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Alternative names
SLC27A2 antibody; ACSVL1 antibody; FACVL1 antibody; FATP2 antibody; HsT17226 antibody; VLACS antibody; VLCS antibody; hFACVL1 antibody; solute carrier family 27 member 2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-200 of human SLC27A2 (NP_001153101.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:50 - 1:200 -
Validations
Western blot - SLC27A2 Polyclonal Antibody
Western blot analysis of extracts of HepG2 cells, using SLC27A2 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
Immunohistochemistry - SLC27A2 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human liver using SLC27A2 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SLC27A2 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human gastric cancer using SLC27A2 antibody at dilution of 1:100 (40x lens).
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Background
Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precursors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"