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Product Name
Mouse CD84 (His Tag) recombinant protein
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Description
Plays a role as adhesion receptor functioning by homophilic interactions and by clustering. Recruits SH2 domain-containing proteins SH2D1A/SAP. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway. May serve as a marker for hematopoietic progenitor cells.
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Protein name
SLAM family member 5
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Protein short names
LY9B; DKFZP781E2378; MCD84; SLAMF5; HCD84; CD84; A130013D22RIK; CDW84
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Uniprot ID
Q18PI6
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Gene Name
Cd84; Slamf5
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse CD84 isoform 1 (Q18PI6-1) extracellular domain (Met 1-Val 221) was expressed, with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse CD84 consists of 211 amino acids and has a predicted molecular mass of 24 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmCD84 is approximately 37-42 kDa due to glycosylation.
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Purity
> 97 % as determined by SDS-PAGE
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Activity
Measured by its ability to bind biotinylated recombinant human SH2D1A in a functional ELISA.
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Validations
Mouse CD84 Protein (His Tag) SDS-PAGE
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