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Product Name
Human CD84 (His Tag) recombinant protein
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Description
Plays a role as adhesion receptor functioning by homophilic interactions and by clustering. Recruits SH2 domain-containing proteins SH2D1A/SAP. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway. May serve as a marker for hematopoietic progenitor cells.
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Protein name
SLAM family member 5
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Protein short names
CDW84; A130013D22RIK; CD84; HCD84; SLAMF5; MCD84; DKFZP781E2378; LY9B
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Uniprot ID
Q9UIB8
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Gene Name
CD84; SLAMF5
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain (Met 1-Gly 225) of human CD84 (NP_003865.1) was expressed with a C-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The recombinant human CD84 consists of 215 amino acids and has a predicted molecular mass of 24 kDa. As a result of glycosylation, the apparent molecular mass of rhCD84 is approximately 45 kDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human CD84 Protein (His Tag) SDS-PAGE
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