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Product Name
SFTPC antibody
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Description
SFTPC Rabbit Polyclonal antibody. Positive IHC detected in human lung cancer tissue, human testis tissue. Positive WB detected in A549 cells. Observed molecular weight by Western-blot: 21-25 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human, Rat; other species not tested.
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Alternative names
PSP C antibody; SFTP2 antibody; SFTPC antibody; SMDP2 antibody; SP C antibody; SP5 antibody; surfactant protein C antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SFTPC recombinant protein (Accession Number: NM_001385653). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IHC: 1:20-1:200
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Validations
A549 cells were subjected to SDS PAGE followed by western blot with Catalog No:115158(SFTPC antibody) at dilution of 1:300
Immunohistochemical of paraffin-embedded human lung cancer using Catalog No:115158(SFTPC antibody) at dilution of 1:50 (under 40x lens)
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Background
SFTPC (surfactant protein C), also named as SFTP2, SP5 and SP-C, is a pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. Defects in SFTPC are the cause of pulmonary surfactant metabolism dysfunction type 2 (SMDP2). Genetic variations in SFTPC are associated with respiratory distress syndrome in premature infants (RDS). Two isoforms of the human protein are produced by alternative splicing, this antibody (catalog#10774-1-AP) is a rabbit polyclonal antibody raised with the full-length SFTPC of huam origin.
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References
- Grisafi D, Pozzobon M, Dedja A. Human amniotic fluid stem cells protect rat lungs exposed to moderate hyperoxia. Pediatric pulmonology. 48(11):1070-80. 2013.
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