-
Product Name
Human SCG3 / Secretogranin 3 (His Tag) recombinant protein
- Documents
-
Description
SCG3, also known as secretogranin 3, is a member of the chromogranin/secretogranin family. Members of this family may serve as precursors for biologically active peptides. SCG3 is transported to secretory granules (SGs) in neuroendocrine cells. SCG3 binds strongly to chromogranin A (CgA) in an intragranular milieu and targets CgA to SGs in pituitary and pancreatic endocrine cells. With a sucrose density gradient of rat insulinoma-derived INS-1 cell homogenates, SgIII is localized to the SG fraction and is fractionated to the SG membrane (SGM) despite lacking the transmembrane region.
-
Protein name
Secretogranin-3
-
Protein short names
SECRETOGRANIN III; SECRETOGRANIN-3; SCG3; UNQ2502/PRO5990; AI385542; 1B1075; SGIII; CHGD
-
Uniprot ID
Q8WXD2
-
Gene Name
SCG3; UNQ2502/PRO5990
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the human SCG3 (AAH14539.1) (Met1-Leu468) was expressed with a C-terminal polyhistidine tag.
-
Protein Species
Human
-
Molecular weight
The recombinant human SCG3 comprises 460 amino acids and has a predicted molecular mass of 52.4 kDa. The apparent molecular mass of the protein is approximately 54-63 kDa in SDS-PAGE under reducing conditions.
-
Purity
> 95 % as determined by SDS-PAGE
-
Validations
Human SCG3 / Secretogranin 3 Protein (His Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"