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Product Name
Mouse SCG3 / Secretogranin 3 (His Tag) recombinant protein
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Description
SCG3, also known as secretogranin 3, is a member of the chromogranin/secretogranin family. Members of this family may serve as precursors for biologically active peptides. SCG3 is transported to secretory granules (SGs) in neuroendocrine cells. SCG3 binds strongly to chromogranin A (CgA) in an intragranular milieu and targets CgA to SGs in pituitary and pancreatic endocrine cells. With a sucrose density gradient of rat insulinoma-derived INS-1 cell homogenates, SgIII is localized to the SG fraction and is fractionated to the SG membrane (SGM) despite lacking the transmembrane region.
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Protein short names
SGIII; SECRETOGRANIN-3; SCG3; CHGD; UNQ2502/PRO5990; AI385542; SECRETOGRANIN III; 1B1075
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Uniprot ID
P47867
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse Scg3 (NP_033156.1) (Met1-Leu471) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse Scg3 consists of 460 amino acids and predicts a molecular mass of 52.4 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Mouse SCG3 / Secretogranin 3 Protein (His Tag)
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