SDHC Rabbit Polyclonal antibody. Positive IHC detected in human breast cancer tissue. Positive WB detected in human liver tissue, HepG2 cells, MCF7 cells, mouse lung tissue. Observed molecular weight by Western-blot: 15kd
ELISA, WB, IHC
Human,Mouse,Rat; other species not tested.
CYB560 antibody; CYBL antibody; PGL3 antibody; QPs 1 antibody; QPS1 antibody; SDH3 antibody; SDHC antibody
This antibody was obtained by immunization of SDHC recombinant protein (Accession Number: NM_003001). Purification method: Antigen affinity purified.
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20℃. DO NOT ALIQUOT
human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:115033(SDHC antibody) at dilution of 1:400
Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:115033(SDHC antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:115033(SDHC antibody) at dilution of 1:100 (under 40x lens)
SDHC(Succinate dehydrogenase cytochrome b560 subunit, mitochondrial) is also named as CYB560, SDH3 and belongs to the cytochrome b560 family. It is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Defects in SDHC are the cause of paragangliomas type 3 (PGL3) and paraganglioma and gastric stromal sarcoma (PGGSS). It has a transit peptide of 29 amino acid and has 5 isoforms produced by alternative splicing.
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