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Product Name
SCUBE3 antibody
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Description
SCUBE3 Rabbit Polyclonal antibody. Positive WB detected in mouse kidney tissue, mouse lung tissue. Positive IHC detected in human kidney tissue. Observed molecular weight by Western-blot: 130kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CEGF3 antibody; DKFZp686B09105 antibody; DKFZp686B1223 antibody; DKFZp686D20108 antibody; FLJ34743 antibody; SCUBE3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SCUBE3 recombinant protein (Accession Number: NM_001303136). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IHC: 1:20-1:200
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Validations
mouse kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:115022(SCUBE3 antibody) at dilution of 1:300
Immunohistochemical of paraffin-embedded human kidney using Catalog No:115022(SCUBE3 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human kidney using Catalog No:115022(SCUBE3 antibody) at dilution of 1:50 (under 40x lens)
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Background
SCUBE3 is a secreted glycoprotein that belongs to the SCUBE family. Members of the SCUBE family are secreted plasma membrane-associated proteins characterised by a N-terminal signal peptide sequence, multiple EGF domains, a N-linked glycosylated spacer region and a C-terminal CUB region. SCUBE3 may play a role in bone cell biology (PMID: 15234972). It may also has a role in the regulation of cardiac growth and remodeling responses (PMID: 17442284). Besides, SCUBE3 has been reported to be involved in lung cancer progression (PMID: 21441952; 23420440).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"