-
Product Name
SCO2 Polyclonal Antibody
- Documents
-
Description
Polyclonal antibody to SCO2
-
Tested applications
WB, IHC
-
Species reactivity
Human, Mouse, Rat
-
Alternative names
SCO2 antibody; CEMCOX1 antibody; MYP6 antibody; SCO1L antibody; protein SCO2 homolog, mitochondrial antibody
-
Isotype
Rabbit IgG
-
Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human SCO2 (NP_001162582.1).
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
-
Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
-
Applications
WB 1:500 - 1:2000
IHC 1:50 - 1:200 -
Validations
Western blot - SCO2 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using SCO2 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit .Exposure time: 3min.
Immunohistochemistry - SCO2 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human stomach using SCO2 Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SCO2 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat brain using SCO2 Antibody at dilution of 1:100 (40x lens).
-
Background
Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"