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Product Name
RPE65 antibody
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Description
RPE65 Rabbit Polyclonal antibody. Positive WB detected in Y79 cells, HeLa cells, mouse eye tissue, PC-3 cells. Observed molecular weight by Western-blot: 65kd,61kd
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
LCA2 antibody; mRPE65 antibody; rd12 antibody; Retinoid isomerohydrolase antibody; Retinol isomerase antibody; RP20 antibody; RPE65 antibody; sRPE65 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of RPE65 recombinant protein (Accession Number: NM_000329). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
Y79 cells were subjected to SDS PAGE followed by western blot with Catalog No:114802(RPE65 antibody) at dilution of 1:600
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Background
RPE65(Retinal pigment epithelium-specific 65 kDa protein) is also named as retinoid isomerohydrolase with the calculated molecular weight og 61 kDa and belongs to the carotenoid oxygenase family. It is a microsomal protein with isomerase activity in the retinoid visual cycle that playing a role in the isomerisation of all-trans (vitamin A) to 11-cis retinal, the chromophore of the visual pigments. It also might be involved in retinoid uptake of keratinocytes.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"