-
Product Name
RORB antibody
- Documents
-
Description
RORB Rabbit Polyclonal antibody. Positive IHC detected in mouse brain tissue. Positive IP detected in mouse brain tissue. Positive WB detected in Y79 cells, mouse brain tissue, SH-SY5Y cells. Observed molecular weight by Western-blot: 52 kDa
-
Tested applications
ELISA, WB, IHC, IP
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
bA133M9.1 antibody; NR1F2 antibody; Nuclear receptor ROR beta antibody; Nuclear receptor RZR beta antibody; RAR related orphan receptor B antibody; ROR BETA antibody; RORB antibody; RZR BETA antibody; RZRB antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of RORB recombinant protein (Accession Number: NM_006914). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
IHC: 1:20-1:200
-
Validations
Y79 cells were subjected to SDS PAGE followed by western blot with Catalog No:114789(RORB antibody) at dilution of 1:800
IP Result of anti-RORB (IP:Catalog No:114789, 4ug; Detection:Catalog No:114789 1:300) with mouse brain tissue lysate 3440ug.
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:114789(RORB Antibody) at dilution of 1:200 (under 40x lens)
-
Background
Nuclear receptors (NRs) are a large group of ligand-inducible transcription factors that regulate many facets of mammalian Physiology [PMID:22189870]. In addition, NRs that lack identified ligands and are termed orphan receptors. RORB is a transcription factor and belongs to the nuclear receptor family [PMID:7935491], which share a common modular structure composed of a transactivation domain, a DNA-binding domain, and a ligand-binding. Its function as transcriptional factor is regulated by small lipophilic molecules, such as steroid hormones, vitamin D, retinoic acids, and thyroid hormone [PMID:17431400].
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"