RNGTT antibody

Cat.#: 114766

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Product Information

  • Product Name
    RNGTT antibody
  • Documents
  • Description
    RNGTT Rabbit Polyclonal antibody. Positive WB detected in human kidney tissue. Positive IP detected in mouse kidney tissue. Observed molecular weight by Western-blot: 69 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    CAP1A antibody; DKFZp686J2031 antibody; GTase antibody; GTP RNA guanylyltransferase antibody; hCAP antibody; HCAP1 antibody; HCE antibody; HCE1 antibody; mRNA 5 triphosphatase antibody; mRNA capping enzyme antibody; RNGTT antibody; TPase mRNA guanylyltransferase antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of RNGTT recombinant protein (Accession Number: NM_003800). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IP: 1:200-1:2000

  • Validations

    human kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:114766(RNGTT antibody) at dilution of 1:800

    human kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:114766(RNGTT antibody) at dilution of 1:800

    IP Result of anti-RNGTT (IP:Catalog No:114766, 4ug; Detection:Catalog No:114766 1:500) with mouse kidney tissue lysate 4000ug.

    IP Result of anti-RNGTT (IP:Catalog No:114766, 4ug; Detection:Catalog No:114766 1:500) with mouse kidney tissue lysate 4000ug.

  • Background
    RNGTT(mRNA-capping enzyme) is also named as HCAP1, HCE, CAP1A. In the N-terminal section it belongs to the non-receptor class of the protein-tyrosine phosphatase family and in the C-terminal section it belongs to the eukaryotic GTase family. It is a bifunctional 597-amino acid protein with RNA triphosphatase and RNA guanylyltransferase activities(PMID:9545288). It has 4 isoforms produced by alternative splicing.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"