RNF170 antibody

RNF170 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

RNF170 Rabbit Polyclonal antibody. Positive IHC detected in human breast cancer tissue, human kidney tissue. Positive WB detected in human brain tissue, human placenta tissue. Observed molecular weight by Western-blot: 27kd

ELISA, WB, IHC

Human; other species not tested.

DKFZp564A022 antibody; FLJ38306 antibody; ring finger protein 170 antibody; RNF170 antibody

Rabbit IgG

This antibody was obtained by immunization of RNF170 recombinant protein (Accession Number: NM_001160224). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

RNF17 also termed as ring finger protein 17 is a 1623 amino acid protein, which contains 1 ring type zinc finger and 4 tudor domains. RNF17 is specifically expressed in testis. The RING finger motif presents in many ubiquitin E3 ligases. RNF17 interacts with all four members of the Mad family (Mad1, Mxi1, Mad3 and Mad4), which are basic-helix-loop-helix-leucine zipper transcription factors of the Myc oncoprotein network. RNF17 is component of the tectonic-like complex, which is required for ciliogenesis and sonic hedgehog/SHH signaling. RNF17 is able to form dimers or polymers both in vitro and in vivo, indicating that it may play a role in the assembly of RNF17 granules. RNF17 encodes a novel key regulator of spermiogenesis.