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Product Name
Mouse RBP4 (His Tag) recombinant protein
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Description
Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
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Protein name
Retinol-binding protein 4
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Protein short names
RBP4; PRO2222; RBPA; OTTHUMP00000020115; RBP-4; PRBP; RDCCAS; RBP
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Uniprot ID
Q00724
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Gene Name
Rbp4
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse RBP4 (NP_035385.1) (Met 1-Leu 201) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse RBP4 comprises 194 amino acids and has a predicted molecular mass of 22.8 kDa as estimated in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Measured by its ability to bind alltrans retinoic acid. The binding of retinoic acid results in the quenching of Trp fluorescence in RBP4.
The 50% binding concentration (BC50) is >0.5 µM -
Validations
Mouse RBP4 Protein (His Tag) SDS-PAGE
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