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Product Name
Human RBP4 (His Tag) recombinant protein
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Description
Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
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Protein name
Retinol-binding protein 4
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Protein short names
PRBP; RBP-4; OTTHUMP00000020115; RBPA; RBP; RDCCAS; PRO2222; RBP4
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Uniprot ID
P02753
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Gene Name
RBP4; PRO2222
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the pro form of human RBP4 (NP_006735.2) (Met 1-Leu 201) was expressed with a C-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The recombinant human RBP4 consists of 194 amino acids after removal of the signal peptide and migrates as an approximately 23 kDa protein as predicted.
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Purity
> 85 % as determined by SDS-PAGE
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Activity
Measured by its ability to bind all-trans retinoic acid. The binding of retinoic acid results in the quenching of Trp fluorescence in RBP4.
The 50% binding concentration (BC50) is > 1.0 µM. -
Validations
Human RBP4 Protein (His Tag) SDS-PAGE
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