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Product Name
Mouse Nogo Receptor (His Tag) recombinant protein
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Description
Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system (By similarity). Acts in conjunction with RTN4 and LIGO1 in regulating neuronal precursor cell motility during cortical development.
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Protein name
Reticulon-4 receptor
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Protein short names
NGR; UNQ330/PRO526; NGR1; NOGOR
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Uniprot ID
Q99PI8
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Gene Name
Rtn4r; Nogor
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of mouse RTN4R (NP_075358.1) (Met 1-Ser 447) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted mature form of mouse RTN4R consists of 432 amino acids and has a predicted molecular mass of 47 kDa. Due to glycosylation, rmRTN4R migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 97 % as determined by SDS-PAGE
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Activity
1. Measured by its binding ability in a functional ELISA.
2. Immobilized recombinant Mouse RTN4R at 2 μg/ml (100 μl/well) can bind biotinylated human RTN4 (GST Tag) with a linear range of 0.04-0.625 μg/ml. -
Validations
Mouse Nogo Receptor / NOGOR / RTN4R Protein (His Tag) SDS-PAGE
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