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Product Name
Human RTN4R/NOGOR/UNQ330/PRO526 (His tag) recombinant protein
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Description
Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be proposed as a potential drug target for treatment of various neurological conditions. Additionally, NgR may play a role in regulating the function of gap junctions.
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Protein name
reticulon 4 receptor(RTN4R)
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Protein short names
NOGOR; UNQ330; PRO526
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Uniprot ID
Q9BZR6
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human RTN4R/NOGOR/UNQ330/PRO526 Cys27-Ser447 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human RTN4R/NOGOR/UNQ330/PRO526 (His tag) recombinant protein
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