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  • Rat Il1a recombinant protein

Rat Il1a recombinant protein

Cat.#: 519528

Special Price 156.8 USD

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Product Information

  • Product Name
    Rat Il1a recombinant protein
  • Documents
  • Description
    Interleukin 1 (IL-1) is a name that designates two proteins, IL-1αand IL-1β, which are the products of distinct genes, but which show approximately 25% amino acid (aa) sequence identity and which recognize the same cell surface receptors. IL-1αand IL-1β are both synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17,000 Da. Neither precursor contains a typical hydrophobic signal peptide sequence and most of the precursor form of IL-1α remains in the cytosol of cells, although there is evidence for a membranebound form of the precursor form of IL-1α. Although IL-1 production is generally considered to be a consequence of inflammation, evidence suggests that IL-1 is also temporally upregulated during bone formation and the menstrual cycle and can be induced in response to nervous system stimulation. In response to classic stimuli produced by inflammatory agents, infections or microbial endotoxins, a dramatic increase in the production of IL-1 by macrophages and various other cells is seen.
  • Protein name
    interleukin 1 alpha(Il1a)
  • Uniprot ID
    P16598
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Rat Il1a Ser115-Ser270 is expressed.
  • Protein Species
    Rat
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Rat Il1a recombinant protein

    Rat Il1a recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"