Anti-IL1A antibody

Anti-IL1A antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Mouse IL1A

WB, ELISA, IP

Mouse IL1A/IL-1A/IL-1F1

IL-1F1 antibody; IL1 antibody; IL-1 alpha antibody; IL1A antibody; IL-1A antibody; IL1-ALPHA antibody; IL1F1 antibody; Il-1a antibody; IL1 antibody; IL-1A antibody; IL1F1 antibody; IL1-ALPHA antibody; Il-1a antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Mouse IL1A/IL-1A/IL-1F1 . IL1A/IL-1A/IL-1F1 specific IgG was purified by Mouse IL1A/IL-1A/IL-1F1 affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. Cytokines can be classified into two groups: pro- and anti-inflammatory. Pro-inflammatory cytokines, including IFNgamma, IL-1, IL-6 and TNF-alpha, are predominantly derived from the innate immune cells and Th1 cells. Anti-inflammatory cytokines, including IL-10, IL-4, IL-13 and IL-5, are synthesized from Th2 immune cells. IL-1 alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. It is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy