Human IL-1 alpha / IL-1F1 / IL1A recombinant protein

Cat.#: 502247

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Product Information

  • Product Name
    Human IL-1 alpha / IL-1F1 / IL1A recombinant protein
  • Documents
  • Description
    Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
  • Protein name
    Interleukin-1 alpha
  • Protein short names
    IL1; IL-1 ALPHA; IL1-ALPHA; IL1F1; IL1A; IL-1A
  • Uniprot ID
    P01583
  • Gene Name
    IL1A; IL1F1
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    The processed form of human IL1? (NP_000566.3) (Ser 113-Ala 271) was expressed and purified.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human IL1? consists of 159 amino acids and has a predicted molecular mass of 18 kDa. As a result of glycosylation, the apparent molecular mass of rhIL1? is approximately 22 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 for this effect is typically 0.2-1 ng/mL.
  • Validations

    Human IL-1 alpha / IL1A / IL1F1 Protein SDS-PAGE

    Human IL-1 alpha / IL1A / IL1F1 Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"