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Product Name
Rat Csf2/Csfgm (His tag) recombinant protein
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Description
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factorthat can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by anumber of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cellsand fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophageprogenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. Onmature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on nonhematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF canalso stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma andadenocarcinoma cell lines.
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Protein name
colony stimulating factor 2(Csf2)
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Protein short names
Csfgm
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Uniprot ID
P48750
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Rat Csf2/Csfgm Ala18-Lys144 is expressed with a 6His tag at the C-terminus.
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Protein Species
Rat
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Purity
>95% as determined by SDS-PAGE.
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Validations
Rat Csf2/Csfgm (His tag) recombinant protein
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