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Product Name
Human CSF2/GMCSF recombinant protein
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Description
GM-CSF was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic, monocytes/macrophages, and eosinophils, GM-CSF has also been reported to have a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines.
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Protein name
colony stimulating factor 2(CSF2)
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Protein short names
GMCSF
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Uniprot ID
P04141
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Source/Expression Host
Yeast
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CSF2/GMCSF Ala18-Glu144 is expressed.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CSF2/GMCSF recombinant protein
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