-
Product Name
Rat CD81 / TAPA-1 (Fc Tag) recombinant protein
- Documents
-
Description
CD81, also known as TAPA-1, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition.
-
Protein short names
TETRASPANIN-28; CD81; 26 KDA CELL SURFACE PROTEIN TAPA-1; TAPA-1; CVID6; CD81 MOLECULE; CD81 ANTIGEN; S5.7; TSPAN28; CD81 ANTIGEN (TARGET OF ANTIPROLIFERATIVE ANTIBODY 1); TAPA1; TSPAN-28; TARGET OF THE ANTIPROLIFERATIVE ANTIBODY 1
-
Uniprot ID
Q6P9V1
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the rat Cd81 (NP_037219.1) (Lys116-Lys201) was expressed with the Fc region of mouse IgG1 at the N-terminus.
-
Protein Species
Rat
-
Molecular weight
The recombinant rat Cd81 consists 322 amino acids and predicts a molecular mass of 36.2 kDa.
-
Purity
> (83.0+15.4)% as determined by SDS-PAGE.
-
Validations
Rat CD81 / TAPA-1 Protein (Fc Tag)
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"