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Product Name
Rat CD81 / TAPA-1 recombinant protein
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Description
CD81, also known as TAPA-1, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition.
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Protein short names
TARGET OF THE ANTIPROLIFERATIVE ANTIBODY 1; TSPAN-28; TAPA1; S5.7; CD81 ANTIGEN; CD81 MOLECULE; CD81 ANTIGEN (TARGET OF ANTIPROLIFERATIVE ANTIBODY 1); TSPAN28; 26 KDA CELL SURFACE PROTEIN TAPA-1; TETRASPANIN-28; CD81; CVID6; TAPA-1
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Uniprot ID
Q6P9V1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat Cd81 (NP_037219.1) (Lys116-Lys201) was expressed with two additional amino acids (Gly & Pro) at the N-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat Cd81 consists of 88 amino acids and predicts a molecular mass of 9.7 kDa.
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Purity
> 85 % as determined by SDS-PAGE.
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Validations
Rat CD81 / TAPA-1 Protein
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