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Product Name
RAP1GDS1 antibody
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Description
RAP1GDS1 Rabbit Polyclonal antibody. Positive IP detected in mouse brain tissue. Positive WB detected in mouse brain tissue. Positive IHC detected in human gliomas tissue. Observed molecular weight by Western-blot: 66 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
Exchange factor smgGDS antibody; GDS1 antibody; RAP1GDS1 antibody; SMG GDS protein antibody; SmgGDS antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of RAP1GDS1 recombinant protein (Accession Number: NM_021159). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114548(RAP1GDS1 antibody) at dilution of 1:500
IP Result of anti-RAP1GDS1 (IP:Catalog No:114548, 3ug; Detection:Catalog No:114548 1:500) with mouse brain tissue lysate 4000ug.
Immunohistochemical of paraffin-embedded human gliomas using Catalog No:114548(RAP1GDS1 antibody) at dilution of 1:50 (under 10x lens)
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Background
GDS stimulates the GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins), including at least c-Ki-ras p21, smg p21A, smg p21B, rhoA p21 and rhoB p21, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein. The small GTPase Rap1, which is activated by a large variety of stimuli, functions in the control of integrin-mediated cell adhesion. RAP1GDS1 (synonym: GDS1)is one of RAP1 GTP-GDP dissociation stimulators.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"