RACK1 antibody

RACK1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

RACK1 Rabbit Polyclonal antibody. Positive IF detected in HeLa cells. Positive IHC detected in human lung cancer tissue.

ELISA, IHC, IF

Human; other species not tested.

GNB2L1 antibody; H12.3 antibody; HLC 7 antibody; PIG21 antibody; RACK1 antibody

Rabbit IgG

This antibody was obtained by immunization of RACK1 recombinant protein (Accession Number: NM_006098). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. RACK1 (receptor for activated protein kinase C 1), encoded by GNB2L1 gene, is a 317 amino acid guanine nucleotide-binding protein subunit beta-2-like 1 protein which is involved in the recruitment, assembly and/or regulation of a variety of signaling molecules, it contains 7 WD-repeats and is implicated in various protein interaction activities. RACK1 is a component of the 40S ribosomal subunit involved in translational repression. Recent finding suggests that RACK1 may be a new promising diagnosis biomarker and therapeutic target for non-small-cell lung cancer (NSCLC).

• Saba LM, Bennett B, Hoffman PL. A systems genetic analysis of alcohol drinking by mice, rats and men: influence of brain GABAergic transmission. Neuropharmacology. 60(7-8):1269-80. 2011.