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Product Name
RAB8B antibody
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Description
RAB8B Rabbit Polyclonal antibody. Positive IHC detected in human lung cancer tissue, human testis tissue. Positive WB detected in fetal human brain tissue, human brain tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 24 kDa
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Tested applications
ELISA, IHC, WB, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
FLJ38125 antibody; RAB8 antibody; RAB8B antibody; Ras related protein Rab 8B antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of RAB8B recombinant protein (Accession Number: NM_016530). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
IHC: 1:20-1:200
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Validations
fetal human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114461(RAB8B Antibody) at dilution of 1:1000
IP Result of anti-RAB8B (IP:Catalog No:114461, 4ug; Detection:Catalog No:114461 1:1000) with mouse brain tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using Catalog No:114461(RAB8B Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using Catalog No:114461(RAB8B Antibody) at dilution of 1:50 (under 40x lens)
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Background
RAB8B represents RAB8B, member RAS oncogene family
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References
- Bryant DM, Datta A, Rodríguez-Fraticelli AE, Peränen J, Martín-Belmonte F, Mostov KE. A molecular network for de novo generation of the apical surface and lumen. Nature cell biology. 12(11):1035-45. 2010.
- Heidrych P, Zimmermann U, Bress A. Rab8b GTPase, a protein transport regulator, is an interacting partner of otoferlin, defective in a human autosomal recessive deafness form. Human molecular genetics. 17(23):3814-21. 2008.
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