PTHLH Polyclonal Antibody
Polyclonal antibody to PTHLH
WB, IHC, FC
PTHLH antibody; BDE2 antibody; HHM antibody; PLP antibody; PTHR antibody; PTHRP antibody; parathyroid hormone like hormone antibody
Antigen: A synthetic peptide of human PTHLH
PBS with 0.02% sodium azide, pH7.3.
Store at 4℃. Avoid freeze / thaw cycles.
WB 1:500 - 1:1000
IHC 1:50 - 1:100
FC 1:20 - 1:50
Western blot - PTHLH Polyclonal Antibody
Western blot analysis of extracts of mouse spleen, using PTHLH antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath (By similarity). Promotes colon cancer cell migration and invasion in an integrin alpha-6/beta-1-dependent manner through activation of Rac1.; Osteostatin is a potent inhibitor of osteoclastic bone resorption.
Related Products / Services
- Human PTHLH Recombinant protein (His tag)
- Human PTHLH/PTHRP (His tag) recombinant protein
- Human PTHLH Recombinant protein (GST tag)
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"